Genomic Feature
hu3378
- ID
- ZDB-ALT-100514-18
- Name
- hu3378
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Hubrecht Institute
- Current Source
- European Zebrafish Resource Center (EZRC) ( order this )
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 5: 68450094 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- A>T (1)
- Transcript Consequence
- None
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
---|---|---|---|---|---|
ephb4ahu3378/hu3378 | Homozygous | ♀+/- ♂+/- | Fig. 7 ![]() | ||
ephb4ahu3378 | Unknown | Unknown |
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Supplemental Information
- Genotyping protocol
- None
- Thestrup, M.I., Caviglia, S., Cayuso, J., Heyne, R.L.S., Ahmad, R., Hofmeister, W., Satriano, L., Wilkinson, D.G., Andersen, J.B., Ober, E.A. (2019) A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation. Nature communications. 10:5220
- Choe, C.P., Crump, J.G. (2015) Eph-Pak2a signaling regulates branching of the pharyngeal endoderm by inhibiting late-stage epithelial dynamics. Development (Cambridge, England). 142(6):1089-94
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