Genomic Feature
hi1241Tg
- ID
- ZDB-ALT-040721-30
- Name
- hi1241Tg
- Synonyms
-
- hi1241 (1)
- Affected Genomic Region
- Construct
- Type
- Allele caused by Transgenic insertion (1)
- Protocol
- embryos treated with DNA
- Lab of Origin
- Hopkins Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
| Comment | Citation |
|---|---|
| The construct was inserted on the minus strand of the genome. The gene in which ... | ZFIN Curated Data |
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 25: 13403347 - 13403348 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- Insertion in Intron 1 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| gins3hi1241Tg/hi1241Tg | Homozygous | Unknown | text only from Amsterdam et al., 2004 | ||
| gins3hi1241Tg/+ (AB) | Heterozygous | Unknown | |||
| gins3hi1241Tg/+ (AB/TU) | Heterozygous | Unknown | |||
| gins3hi1241Tg | Unknown | Unknown | 2 figures  from 2 publications |
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Supplemental Information
- Genotyping protocol
- None
- Milan, D.J., Kim, A.M., Winterfield, J.R., Jones, I.L., Pfeufer, A., Sanna, S., Arking, D.E., Amsterdam, A.H., Sabeh, K.M., Mably, J.D., Rosenbaum, D.S., Peterson, R.T., Chakravarti, A., Kääb, S., Roden, D.M., and MacRae, C.A. (2009) Drug-Sensitized Zebrafish Screen Identifies Multiple Genes, Including GINS3, as Regulators of Myocardial Repolarization. Circulation. 120(7):553-559
- Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
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