| ZFIN ID: ZDB-EXP-240712-1 |
Experiment Conditions Description: cold damage: heart, chemical treatment by environment: Human Heregulin-b1
| cold damage: heart |
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| Name: | cold damage |
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| Synonyms: | |
| Definition: | Physical alteration which uses cold to damage an anatomical structure, cell, or organ |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000248] |
| Name: | heart |
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| Synonyms: | |
| Definition: | Blood pumping organ composed of four components: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus. |
| Ontology: | Anatomy Ontology [ZFA:0000114] |
| chemical treatment by environment: Human Heregulin-b1 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | Human Heregulin-b1 |
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| Synonyms: | HRG, Neuregulin-1, Neuregulin1, NRG1, Peprotech 100-03 |
| Definition: | Neuregulin/Heregulin is a family of structurally-related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extracellular domain of the transmembrane NRG1 isoforms releases soluble growth factors. Amino acid sequence: SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQNYVM ASFYKHLGIE FMEAE |
| Ontology: | ChEBI [CHEBI:231555] ( EBI ) |
| Publication: | de Bakker et al., 2021 |
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