| ZFIN ID: ZDB-EXP-240103-15 |
Experiment Conditions Description: chemical treatment by environment: SU5402, organ culture: heart
| chemical treatment by environment: SU5402 |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | SU5402 |
|---|---|
| Synonyms: | 3-[3-(2-carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone, 3-{4-methyl-2-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid, 3-{[3-(2-carboxyethyl)-4-methylpyrrol-2-yl]methylene}-2-indolinone, SU 5402, Su-5402 |
| Definition: | An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 3-(2-carboxyethyl)-4-methyl-1H-pyrrol-2-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1. |
| Ontology: | ChEBI [CHEBI:63449] ( EBI ) |
| organ culture: heart |
|---|
| Name: | organ culture |
|---|---|
| Synonyms: | |
| Definition: | In vitro culture condition in which an organ is dissected/isolated/collected from the fish and placed in culture. The analysis of the experiment is done on this organ in culture. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000144] |
| Name: | heart |
|---|---|
| Synonyms: | |
| Definition: | Blood pumping organ composed of four components: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus. |
| Ontology: | Anatomy Ontology [ZFA:0000114] |
| Publication: | Tessadori et al., 2021 |
|---|