| ZFIN ID: ZDB-EXP-231025-8 |
Experiment Conditions Description: chemical treatment by injection: busulfan
| chemical treatment by injection: busulfan |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | busulfan |
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| Synonyms: | 1,4-Bis(methanesulfonoxy)butane, 1,4-Butanediol dimethanesulfonate, 1,4-Dimesyloxybutane, 1,4-Dimethanesulfonoxybutane, Bisulfex, busulfan, busulfano, busulfanum, butane-1,4-diyl dimethanesulfonate, Leucosulfan, Mablin, Mielucin, Misulban, Mitostan, Myeloleukon, Myleran, Tetramethylene bis(methanesulfonate) |
| Definition: | A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant. |
| Ontology: | ChEBI [CHEBI:28901] ( EBI ) |
| Publication: | Crespo et al., 2021 |
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