| ZFIN ID: ZDB-EXP-220222-12 |
Experiment Conditions Description: chemical treatment by injection: lipopolysaccharide, chemical treatment by environment: indometacin
| chemical treatment by injection: lipopolysaccharide |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | lipopolysaccharide |
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| Synonyms: | Lipopolysaccharide, lipopolysaccharides, LPS |
| Definition: | Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). |
| Ontology: | ChEBI [CHEBI:16412] ( EBI ) |
| chemical treatment by environment: indometacin |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | indometacin |
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| Synonyms: | 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid, Aconip, Indocin, indometacin, indometacina, indometacine, indometacinum, Indomethacin, {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid |
| Definition: | A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. |
| Ontology: | ChEBI [CHEBI:49662] ( EBI ) |
| Publication: | Luo et al., 2019 |
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