ZFIN ID: ZDB-EXP-211104-2
Experiment Conditions Description: chemical treatment: CFTRinh-172
chemical treatment: CFTRinh-172
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: CFTRinh-172
Synonyms: (inh)-172, 3-[(3-trifluoromethyl)phenyl]-5-[(3-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone, 4-({4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl)benzoic acid, 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone, C2992_SIGMA, CFTR(inh)-172, Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172, cystic fibrosis transmembrane regulator inhibitor 172
Definition: A thiazolidinone that is 2-thioxo-4-thiazolidinone which is substituted at position 3 by a (m--trifluoromethyl)phenyl group and at position 5 by a p-carboxybenzylidene group. It is an inhibitor of cystic fibrosis transmembrane conductance regulator, a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene.
Ontology: ChEBI [CHEBI:131686]  ( EBI )
Publication: Liu et al., 2020