ZFIN

ZFIN ID: ZDB-EXP-210421-5

Experiment Conditions Description: chemical treatment by injection: amyloid-beta polypeptide 42, chemical treatment: pyrazolotriazine

chemical treatment by injection: amyloid-beta polypeptide 42

Name:	chemical treatment by injection
Synonyms:
Definition:	Chemical treatment in which the chemical is injected into the zebrafish.
Ontology:	Zebrafish Environment Condition Ontology [ZECO:0000237]

Name:	amyloid-beta polypeptide 42
Synonyms:	Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala, beta-amyloid 42, beta-amyloid polypeptide 42, beta-amyloid protein 42, DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA, L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-serylglycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glu
Definition:	A beta-amyloid that ia a 42 amino acid polypeptide of sequence Asp Ala Glu Phe Arg His Asp Ser Gly Tyr Glu Val His His Gln Lys Leu Val Phe Phe Ala Glu Asp Val Gly Ser Asn Lys Gly Ala Ile Ile Gly Leu Met Val Gly Gly Val Val Ile Ala.
Ontology:	ChEBI [CHEBI:64647] ( EBI )

chemical treatment: pyrazolotriazine

Name:	chemical treatment
Synonyms:
Definition:	Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology:	Zebrafish Environment Condition Ontology [ZECO:0000111]

Name:	pyrazolotriazine
Synonyms:	pyrazolotriazine, pyrazolotriazines
Definition:	Any organic heterobicyclic compound where the triazine ring is ortho-fused to a pyrazole ring.
Ontology:	ChEBI [CHEBI:144709] ( EBI )

Publication:	Reinhardt et al., 2019