| ZFIN ID: ZDB-EXP-210324-2 |
Experiment Conditions Description: perforation: retina, chemical treatment by injection: pirfenidone
| perforation: retina |
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| Name: | perforation |
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| Synonyms: | |
| Definition: | Experimental condition in which a hole or break in the membranes of an organ or structure of the body is created. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000178] |
| Name: | retina |
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| Synonyms: | retinas |
| Definition: | Multi-tissue structure that contains the retinal neural layer and the retinal pigmented epithelium, and develops from the optic cup. |
| Ontology: | Anatomy Ontology [ZFA:0000152] |
| chemical treatment by injection: pirfenidone |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | pirfenidone |
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| Synonyms: | 5-methyl-1-phenylpyridin-2(1H)-one, AMR 69, AMR-69, Esbriet, pirfenidona, pirfenidone, pirfenidonum |
| Definition: | A pyridone that is 2-pyridone substituted at positions 1 and 5 by phenyl and methyl groups respectively. An anti-inflammatory drug used for the treatment of idiopathic pulmonary fibrosis. |
| Ontology: | ChEBI [CHEBI:32016] ( EBI ) |
| Publication: | Sharma et al., 2020 |
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