ZFIN ID: ZDB-EXP-210115-4 |
Experiment Conditions Description: chemical treatment by environment: CHIC-35
chemical treatment by environment: CHIC-35 |
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Name: | chemical treatment by environment |
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Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | CHIC-35 |
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Synonyms: | (6S)-2-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide, Compound (S)-35, SIRT1 Inhibitor IV, (S)-35 |
Definition: | An organic heterotricyclic compound resulting from the formal fusion of the 2-3 bond of 5-chloroindole with the 2-3 bond of cycloheptanecarboxamide (the S enantiomer). It is a potent, cell-permeable, metabolically stable and selective inhibitor of the deacetylase SIRT1. |
Ontology: | ChEBI [CHEBI:142489] ( EBI ) |
Publication: | Asad et al., 2019 |
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