ZFIN ID: ZDB-EXP-200113-1 |
Experiment Conditions Description: chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F
chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F |
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Name: | chemical treatment by environment |
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Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | Z-Val-Ala-Asp(OMe)-CH2F |
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Synonyms: | N-[(benzyloxy)carbonyl]-L-valyl-N-[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]-L-alaninamide, pan-caspase inhibitor, Z-L-Val-L-Ala-L-Asp(OMe)-CH2F, Z-VAD(OMe)-FMK, Z-VAD-FMK, Z-Val-Ala-Asp(OMe)-fluoromethyl ketone, Z-Val-Ala-Asp(OMe)-FMK |
Definition: | A tripeptide consisting of Z-Val-Ala-Asp(OMe) in which the C-terminal OH group has been replaced by a fluoromethyl group. An irreversible pan-caspase inhibitor. |
Ontology: | ChEBI [CHEBI:137045] ( EBI ) |
Publication: | Villani et al., 2019 |
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