| ZFIN ID: ZDB-EXP-191114-16 |
Experiment Conditions Description: chemical treatment by environment: efavirenz, chemical treatment by environment: pentetrazol
| chemical treatment by environment: efavirenz |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | efavirenz |
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| Synonyms: | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, (4S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one, (S)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one, (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one, 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one, Efavirenz |
| Definition: | 1,4-Dihydro-2H-3,1-benzoxazin-2-one substituted at the 4 position by cyclopropylethynyl and trifluoromethyl groups (S configuration) and at the 6 position by chlorine. A non-nucleoside reverse transcriptase inhibitor with activity against HIV, it is used with other antiretrovirals for combination therapy of HIV infection. |
| Ontology: | ChEBI [CHEBI:119486] ( EBI ) |
| chemical treatment by environment: pentetrazol |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | pentetrazol |
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| Synonyms: | 1,5-pentamethylenetetrazole, 6,7,8,9-tetrahydro-5-azepotetrazole, 6,7,8,9-tetrahydro-5H-tetrazolo[1,5-a]azepine, 7,8,9,10-tetrazabicyclo[5.3.0]-8,10-decadiene, alpha,beta-cyclopentamethylenetetrazole, Cardiazol, Cardiazole, Cardifortan, Cardiotonicum, Cardosal, Cardosan, Cenalene-M, Cenazol, Coranormol, Coratoline, Corazol, Corazole, Corvasol, Coryvet, Deumacard, Diovascole, Gewazol, Kardiazol, Korazol, Metrazol, pentamethylene-1,5-tetrazole, pentetrazol, pentetrazolum, pentylenetetrazol, Pentylenetetrazole, Phrenazol, Ventrazol |
| Definition: | An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis. |
| Ontology: | ChEBI [CHEBI:34910] ( EBI ) |
| Publication: | Sourbron et al., 2019 |
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