| ZFIN ID: ZDB-EXP-190708-20 |
Experiment Conditions Description: chemical treatment by environment: 17alpha-ethynylestradiol, chemical treatment by environment: fulvestrant
| chemical treatment by environment: 17alpha-ethynylestradiol |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | 17alpha-ethynylestradiol |
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| Synonyms: | 17-ethinyl-3,17-estradiol, 17-ethinyl-3,17-oestradiol, 17-ethinylestradiol, 17alpha-Ethinyl estradiol, 17alpha-ethynylestra-1,3,5(10)-triene-3,17beta-diol, 17alpha-ethynylestradiol, Ethinyl estradiol, Ethinylestradiol, ethinyloestradiol, Ethynyl estradiol |
| Definition: | A 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration. |
| Ontology: | ChEBI [CHEBI:4903] ( EBI ) |
| chemical treatment by environment: fulvestrant |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | fulvestrant |
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| Synonyms: | (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol, 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol, Faslodex, fulvestrant, fulvestrantum, ICI 182780, ICI-182780 |
| Definition: | A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer. |
| Ontology: | ChEBI [CHEBI:31638] ( EBI ) |
| Publication: | Carroll et al., 2014 |
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