ZFIN ID: ZDB-EXP-190321-1
Experiment Conditions Description: chemical treatment by environment: cisplatin
chemical treatment by environment: cisplatin
Name: chemical treatment by environment
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: cisplatin
Synonyms: (SP-4-2)-diamminedichloridoplatinum, (SP-4-2)-diamminedichloroplatinum, [PtCl2(NH3)2], Briplatin, CDDP, cis-[PtCl2(NH3)2], cis-DDP, cis-diamminedichloridoplatinum(II), cis-diamminedichloroplatinum, cis-Diamminedichloroplatinum(II), cis-diammineplatinum(II) dichloride, cis-dichlorodiammineplatinum(II), cis-platin, Cismaplat, Cisplatin, cisplatine, cisplatino, cisplatinum, Lederplatin, Neoplatin, Peyrone's chloride, Peyrone's salt, Platamine, Platinex, Platinol, Randa
Definition: A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).
Ontology: Chebi [CHEBI:27899]
Publication: Sanchez et al., 2018