ZFIN ID: ZDB-EXP-180725-5
Experiment Conditions Description: chemical treatment by injection: tyloxapol
chemical treatment by injection: tyloxapol
Name: chemical treatment by injection
Synonyms:
Definition: Chemical treatment in which the chemical is injected into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000237]
Name: tyloxapol
Synonyms: 4-(1,1,2,2-tetramethylbutyl)phenol polyer with formaldehyde and oxirane, Alevaire, oxyethylated tertiary octylphenol formaldehyde polymer, p-(1,1,3,3-tetramethylbutyl)phenol polymer with ethylene oxide and formaldehyde, p-isooctylpolyoxyethylenenphenol formaldehyde polymer, Superinone, tiloxapol, Triton A-20, Triton WR-1339, tyloxapol, tyloxapolum, tyloxypal
Definition: A polymeric compound resulting from the reaction of 4-(1,1,3,3-tetramethylbutyl)phenol with formaldehyde to give a chain in which 6-8 molecules are linked together by CH2 groups ortho to the phenolic hydroxy groups, which have then undergone reaction with oxirane to give polyoxyethyleneoxy moieties, Ar(OCH2CH2)xOH, where x = 8-10. A nonionic liquic polymer, it inhibits lipoprotein lipase and hence clearance of triglyceride from the plasma, so is used to induce hyperlipidaemia in test animals. Also used as a surfactant to aid liquefaction and removal of mucus- and pus-containing bronchopulmonary secretions.
Ontology: ChEBI [CHEBI:141517]  ( EBI )
Publication: Benítez-Santana et al., 2017