| ZFIN ID: ZDB-EXP-180724-3 |
Experiment Conditions Description: amputation: caudal fin, chemical treatment: EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor
| amputation: caudal fin |
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| Name: | amputation |
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| Synonyms: | |
| Definition: | Resection condtion in which all or part of an extremity such as the fin or tail are removed. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000172] |
| Name: | caudal fin |
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| Synonyms: | tail, tail fin |
| Definition: | Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines. |
| Ontology: | Anatomy Ontology [ZFA:0001058] |
| chemical treatment: EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor |
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| Synonyms: | ATP:protein phosphotransferase (MAPKKK-activated) inhibitor, ATP:protein phosphotransferase (MAPKKK-activated) inhibitors, EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitors, EC 2.7.12.2 inhibitor, EC 2.7.12.2 inhibitors, MAP kinase kinase 4 inhibitor, MAP kinase kinase 4 inhibitors, MAP kinase kinase 7 inhibitor, MAP kinase kinase 7 inhibitors, MAP kinase kinase inhibitor, MAP kinase kinase inhibitors, MAP kinase or ERK kinase inhibitor, MAP kinase or ERK kinase inhibitors, MAP2K inhibitor, MAP2K inhibitors, MAPKK inhibitor, MAPKK inhibitors, MAPKK1 inhibitor, MAPKK1 inhibitors, MEK inhibitor, MEK inhibitors, MEK1 inhibitor, MEK1 inhibitors, MEK2 inhibitor, MEK2 inhibitors, mitogen-activated protein kinase kinase (EC 2.7.12.2) inhibitor, mitogen-activated protein kinase kinase (EC 2.7.12.2) inhibitors, mitogen-activated protein kinase kinase inhibitor, mitogen-activated protein kinase kinase inhibitors, MKK inhibitor, MKK inhibitors, MKK2 inhibitor, MKK2 inhibitors, MKK4 inhibitor, MKK4 inhibitors, MKK6 inhibitor, MKK6 inhibitors, MKK7 inhibitor, MKK7 inhibitors, STK27 inhibitor, STK27 inhibitors |
| Definition: | An EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor that inhibits the action of mitogen-activated protein kinase kinase (EC 2.7.12.2). |
| Ontology: | ChEBI [CHEBI:88286] ( EBI ) |
| Publication: | Hale et al., 2017 |
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