| ZFIN ID: ZDB-EXP-171222-14 |
Experiment Conditions Description: chemical treatment by environment: pentetrazol, chemical treatment by environment: NMDA receptor antagonist
| chemical treatment by environment: pentetrazol |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | pentetrazol |
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| Synonyms: | 1,5-pentamethylenetetrazole, 6,7,8,9-tetrahydro-5-azepotetrazole, 6,7,8,9-tetrahydro-5H-tetrazolo[1,5-a]azepine, 7,8,9,10-tetrazabicyclo[5.3.0]-8,10-decadiene, alpha,beta-cyclopentamethylenetetrazole, Cardiazol, Cardiazole, Cardifortan, Cardiotonicum, Cardosal, Cardosan, Cenalene-M, Cenazol, Coranormol, Coratoline, Corazol, Corazole, Corvasol, Coryvet, Deumacard, Diovascole, Gewazol, Kardiazol, Korazol, Metrazol, pentamethylene-1,5-tetrazole, pentetrazol, pentetrazolum, pentylenetetrazol, Pentylenetetrazole, Phrenazol, Ventrazol |
| Definition: | An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis. |
| Ontology: | ChEBI [CHEBI:34910] ( EBI ) |
| chemical treatment by environment: NMDA receptor antagonist |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | NMDA receptor antagonist |
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| Synonyms: | N-methyl-D-aspartate receptor antagonist, N-methyl-D-aspartate receptor antagonists, NMDA receptor antagonists, NMDAR antagonist, NMDAR antagonists |
| Definition: | Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. |
| Ontology: | ChEBI [CHEBI:60643] ( EBI ) |
| Publication: | Menezes et al., 2017 |
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