| ZFIN ID: ZDB-EXP-170530-10 |
Experiment Conditions Description: chemical treatment: nomifensine, chemical treatment: oxidopamine
| chemical treatment: nomifensine |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | nomifensine |
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| Synonyms: | (+-)-Nomifensin, (+-)-Nomifensine, 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine, 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine, 8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline, D,L-nomifensine, Nomifenison, Nomifensin, nomifensina, nomifensine, nomifensinum, Nomiphensine, R/S-nomifensine |
| Definition: | An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively. |
| Ontology: | ChEBI [CHEBI:116225] ( EBI ) |
| chemical treatment: oxidopamine |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | oxidopamine |
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| Synonyms: | 2,4,5-trihydroxyphenethylamine, 5-(2-aminoethyl)benzene-1,2,4-triol, 6-hydroxydopamine, 6-OHDA, hydroxydopamine, oxidopamina, oxidopamine, oxidopaminum, topamine |
| Definition: | A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease). |
| Ontology: | ChEBI [CHEBI:78741] ( EBI ) |
| Publication: | Zhang et al., 2017 |
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