| ZFIN ID: ZDB-EXP-150317-6 |
Experiment Conditions Description: high cholesterol, chemical treatment: atorvastatin
| high cholesterol |
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| Name: | high cholesterol |
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| Synonyms: | |
| Definition: | Cholesterol content condition in which the amount of cholesterol in the diet is elevated. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000119] |
| chemical treatment: atorvastatin |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | atorvastatin |
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| Synonyms: | (3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-4-phenyl-2-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid, (R-(R*,R*))-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoic acid, 7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]-3,5-DIHYDROXY-HEPTANOIC ACID, Atorlip, Atorvastatin, atorvastatina, atorvastatine, atorvastatinum |
| Definition: | A dihydroxy monocarboxylic acid that is a member of the drug class known as statins, used primarily for lowering blood cholesterol and for preventing cardiovascular diseases. |
| Ontology: | ChEBI [CHEBI:39548] ( EBI ) |
| Publication: | O'Hare et al., 2014 |
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