ZFIN ID: ZDB-EXP-110923-2
Experiment Conditions Description: chemical treatment: 17beta-estradiol, chemical treatment: fulvestrant
chemical treatment: 17beta-estradiol
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: 17beta-estradiol
Synonyms: (17beta)-estra-1,3,5(10)-triene-3,17-diol, 17beta oestradiol, 17beta-estra-1,3,5(10)-triene-3,17-diol, 17beta-estradiol, 17beta-oestradiol, beta-Estradiol, cis-estradiol, estra-1,3,5(10)-triene-3,17beta-diol, Estradiol, Estradiol-17beta
Definition: The 17beta-isomer of estradiol.
Ontology: Chebi [CHEBI:16469]
chemical treatment: fulvestrant
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: fulvestrant
Synonyms: (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol, 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol, Faslodex, fulvestrant, fulvestrantum, ICI 182780, ICI-182780
Definition: A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer.
Ontology: Chebi [CHEBI:31638]
Publication: Lam et al., 2011