| ZFIN ID: ZDB-EXP-080904-3 |
Experiment Conditions Description: chemical treatment: drug, chemical treatment: cisplatin
| chemical treatment: drug |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | drug |
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| Synonyms: | drugs, medicine |
| Definition: | Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances. |
| Ontology: | ChEBI [CHEBI:23888] ( EBI ) |
| chemical treatment: cisplatin |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | cisplatin |
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| Synonyms: | (SP-4-2)-diamminedichloridoplatinum, (SP-4-2)-diamminedichloroplatinum, [PtCl2(NH3)2], Briplatin, CDDP, cis-[PtCl2(NH3)2], cis-DDP, cis-diamminedichloridoplatinum(II), cis-diamminedichloroplatinum, cis-diamminedichloroplatinum(II), cis-diammineplatinum(II) dichloride, cis-dichlorodiammineplatinum(II), cis-platin, Cismaplat, Cisplatin, cisplatine, cisplatino, cisplatinum, Lederplatin, Neoplatin, Peyrone's chloride, Peyrone's salt, Platamine, Platinex, Platinol, Randa |
| Definition: | A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups). |
| Ontology: | ChEBI [CHEBI:27899] ( EBI ) |
| Publication: | Owens et al., 2008 |
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