| ZFIN ID: ZDB-EXP-261012-6 |
Experiment Conditions Description: bacterial treatment by injection: Streptococcus pneumoniae, primary cell culture: cerebrospinal fluid contacting neuron, bacterial treatment by exposure to environment: Listeria monocytogenes
| bacterial treatment by injection: Streptococcus pneumoniae |
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| Name: | bacterial treatment by injection |
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| Synonyms: | |
| Definition: | Bacterial treatment where the bacteria are injected into the fish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000230] |
| Name: | Streptococcus pneumoniae |
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| Synonyms: | Diplococcus pneumoniae, Micrococcus pneumoniae |
| Definition: | |
| Ontology: | Taxonomy for ZECO [NCBITaxon:1313] |
| primary cell culture: cerebrospinal fluid contacting neuron |
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| Name: | primary cell culture |
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| Synonyms: | |
| Definition: | In vitro culture condition in which an embryo or adult fish is dissociated to a single cell suspension. The analysis is made on this cell culture. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000145] |
| Name: | cerebrospinal fluid contacting neuron |
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| Synonyms: | CSF-cN, CSF-cNs |
| Definition: | Spinal cord interneuron located along the central canal that extends a microvilliated apical process into the cerebrospinal fluid and extends ascending axonal projections ventrally and ipsilaterally. CSF-cNs are GABAergic neurons that express PKD2L1 (TRPP3) channels and have been shown to be chemosensory and mechanosensory, responding to pH and osmolarity changes as well as mechanical stimuli associated with tail bending. CSF-cNs originate from two distinct progenitor domains, p3 and pMN. CSF-cNs project onto caudal primary (CaP motor neurons) and commissural primary ascending (CoPA) sensory interneurons within the escape circuit as well as onto V0-v interneurons within the slow swimming circuit. |
| Ontology: | Anatomy Ontology [ZFA:0007120] |
| bacterial treatment by exposure to environment: Listeria monocytogenes |
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| Name: | bacterial treatment by exposure to environment |
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| Synonyms: | |
| Definition: | Bacterial treatment where the bacteria are introduced via the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000231] |
| Name: | Listeria monocytogenes |
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| Synonyms: | Bacterium monocytogenes, Bacterium monocytogenes hominis, Corynebacterium infantisepticum, Corynebacterium parvulum, Erysipelothrix monocytogenes, Listerella hepatolytica |
| Definition: | |
| Ontology: | Taxonomy for ZECO [NCBITaxon:1639] |
| Publication: | Prendergast et al., 2023 |
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