| ZFIN ID: ZDB-EXP-260407-4 |
Experiment Conditions Description: cancer xenotransplantation, chemical treatment by environment: olaparib
| cancer xenotransplantation |
|---|
| Name: | cancer xenotransplantation |
|---|---|
| Synonyms: | |
| Definition: | Xenotransplantation condition in which cancer cells are injected or grafted into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000236] |
| chemical treatment by environment: olaparib |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | olaparib |
|---|---|
| Synonyms: | 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, AZD-2281, AZD2281, KU59436, Lynparza, olaparib |
| Definition: | A member of the class of N-acylpiperazines obtained by formal condensation of the carboxy group of 2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoic acid with the free amino group of N-(cyclpropylcarbonyl)piperazine; used to treat advanced ovarian cancer. |
| Ontology: | ChEBI [CHEBI:83766] ( EBI ) |
| Publication: | Hayes et al., 2025 |
|---|