ZFIN ID: ZDB-EXP-260121-7
Experiment Conditions Description: bacterial treatment by injection: Mycobacterium marinum M, chemical treatment by injection: Recombinant Tumor Necrosis Factor TNF alpha (Zebrafish), chemical treatment by environment: nigericin
bacterial treatment by injection: Mycobacterium marinum M
Name: bacterial treatment by injection
Synonyms:
Definition: Bacterial treatment where the bacteria are injected into the fish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000230]
Name: Mycobacterium marinum M
Synonyms: Mycobacterium marinum str. M, Mycobacterium marinum strain M
Definition:
Ontology: Taxonomy for ZECO [NCBITaxon:216594]
chemical treatment by injection: Recombinant Tumor Necrosis Factor TNF alpha (Zebrafish)
Name: chemical treatment by injection
Synonyms:
Definition: Chemical treatment in which the chemical is injected into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000237]
Name: Recombinant Tumor Necrosis Factor TNF alpha (Zebrafish)
Synonyms: TNF-a, TNFalpha
Definition: Tumor necrosis factor alpha is a member of the TNF Superfamily. It is produced chiefly by activated macrophages, but it is produced also by a broad variety of cell types including lymphoid cells, mast cells, endothelial cells, cardiac myocytes, adipose tissue, fibroblasts, and neuronal tissue. Protein Sequence:AAIHLTGGYN SESKTLDWRD DQDQAFSSGG LKLVNREIII PDDGIYFVYS QVSLHISCTS ELTEEQVLMS HAVMRFSESY GGKKPLFSAI RSICTQEPES ENLWYNTIYL GAAFHLREGD RLGTDTTTAL LPMVENDNGK TFFGVFGL
Ontology: ChEBI [CHEBI:197439]  ( EBI )
chemical treatment by environment: nigericin
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: nigericin
Synonyms: (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-{(2S,2'R,3'S,5R,5'R)-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-2,3'-dimethyloctahydro-2,2'-bifuran-5-yl}-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl]methyl}, Azalomycin M, Helixin C, Polyetherin A
Definition: A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus.
Ontology: ChEBI [CHEBI:7569]  ( EBI )
Publication: Roca et al., 2022