| ZFIN ID: ZDB-EXP-250618-12 |
Experiment Conditions Description: chemical treatment by environment: paliperidone, chemical treatment by environment: lipopolysaccharide
| chemical treatment by environment: paliperidone |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | paliperidone |
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| Synonyms: | (+-)-paliperidone, (RS)-paliperidone, 9-hydroxy-risperidone, 9-Hydroxyrisperidone, 9-OH-risperidone, Invega, paliperidone, R 76477, R-76477, rac-3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one, rac-paliperidone, racemic paliperidone, Ro-76477, RO76477 |
| Definition: | A racemate comprising equimolar amounts of (R)- and (S)-paliperidone. Paliperidone is the primary active metabolite of the older antipsychotic risperidone and is used for treatment of schizophrenia. |
| Ontology: | ChEBI [CHEBI:82978] ( EBI ) |
| chemical treatment by environment: lipopolysaccharide |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | lipopolysaccharide |
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| Synonyms: | Lipopolysaccharide, lipopolysaccharides, LPS |
| Definition: | Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). |
| Ontology: | ChEBI [CHEBI:16412] ( EBI ) |
| Publication: | Widder et al., 2024 |
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