ZFIN ID: ZDB-EXP-250214-1 |
Experiment Conditions Description: chemical treatment by environment: CID 661578
chemical treatment by environment: CID 661578 |
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Name: | chemical treatment by environment |
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Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | CID 661578 |
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Synonyms: | 7-fluoro-N-(furan-2-ylmethyl)-2-hydroxy-12-methyl-4-oxo-1-azatricyclo[7.3.1.05,13]trideca-2,5,7,9(13)-tetraene-3-carboxamide |
Definition: | CID 661578 targets MAP kinase-interacting serine/threonine kinase 2 (MNK2). CID 661578 increases protein synthesis and regeneration by preventing MNK2 from binding EIF4G in the translation initiation complex at the mRNA cap. |
Ontology: | ChEBI [CHEBI:233083] ( EBI ) |
Publication: | Karampelias et al., 2022 |
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