ZFIN ID: ZDB-EXP-250214-1
Experiment Conditions Description: chemical treatment by environment: CID 661578
chemical treatment by environment: CID 661578
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: CID 661578
Synonyms: 7-fluoro-N-(furan-2-ylmethyl)-2-hydroxy-12-methyl-4-oxo-1-azatricyclo[7.3.1.05,13]trideca-2,5,7,9(13)-tetraene-3-carboxamide
Definition: CID 661578 targets MAP kinase-interacting serine/threonine kinase 2 (MNK2). CID 661578 increases protein synthesis and regeneration by preventing MNK2 from binding EIF4G in the translation initiation complex at the mRNA cap.
Ontology: ChEBI [CHEBI:233083]  ( EBI )
Publication: Karampelias et al., 2022