| ZFIN ID: ZDB-EXP-210526-4 |
Experiment Conditions Description: cancer xenotransplantation, chemical treatment by environment: quininib
| cancer xenotransplantation |
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| Name: | cancer xenotransplantation |
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| Synonyms: | |
| Definition: | Xenotransplantation condition in which cancer cells are injected or grafted into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000236] |
| chemical treatment by environment: quininib |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | quininib |
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| Synonyms: | 2-[(E)-2-(quinolin-2-yl)vinyl]phenol |
| Definition: | A styrylquinoline that is trans-2-styrylquinoline in which the the phenyl group has been substituted at position 2 by a hydroxy group. It is an anti-angiogenic compound that exerts a dose-dependent antagonism of the cysteinyl leukotriene pathway, preferentially antagonising cysteinyl leukotriene receptor 1. The major species at pH 7.3 |
| Ontology: | ChEBI [CHEBI:133170] ( EBI ) |
| Publication: | Slater et al., 2020 |
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