| ZFIN ID: ZDB-EXP-191122-3 |
Experiment Conditions Description: cancer xenotransplantation, chemical treatment by environment: tropomyosin-related kinase B receptor antagonist
| cancer xenotransplantation |
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| Name: | cancer xenotransplantation |
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| Synonyms: | |
| Definition: | Xenotransplantation condition in which cancer cells are injected or grafted into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000236] |
| chemical treatment by environment: tropomyosin-related kinase B receptor antagonist |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | tropomyosin-related kinase B receptor antagonist |
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| Synonyms: | TrkB receptor antagonist, TrkB receptor antagonists, tropomyosin-related kinase B receptor antagonists |
| Definition: | An antagonist that binds to and deactivates the tropomyosin-related kinase B (TrkB) receptor, the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF). |
| Ontology: | ChEBI [CHEBI:78681] ( EBI ) |
| Publication: | Smith et al., 2018 |
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