| ZFIN ID: ZDB-EXP-180828-6 |
Experiment Conditions Description: chemical treatment by environment: oxidopamine, chemical treatment by environment: 17beta-estradiol, chemical treatment by environment: EC 1.14.13.39 (nitric oxide synthase) inhibitor
| chemical treatment by environment: oxidopamine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | oxidopamine |
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| Synonyms: | 2,4,5-trihydroxyphenethylamine, 5-(2-aminoethyl)benzene-1,2,4-triol, 6-hydroxydopamine, 6-OHDA, hydroxydopamine, oxidopamina, oxidopamine, oxidopaminum, topamine |
| Definition: | A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease). |
| Ontology: | ChEBI [CHEBI:78741] ( EBI ) |
| chemical treatment by environment: 17beta-estradiol |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | 17beta-estradiol |
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| Synonyms: | (17beta)-estra-1,3,5(10)-triene-3,17-diol, 17beta oestradiol, 17beta-estra-1,3,5(10)-triene-3,17-diol, 17beta-estradiol, 17beta-oestradiol, beta-Estradiol, cis-estradiol, estra-1,3,5(10)-triene-3,17beta-diol, Estradiol, Estradiol-17beta |
| Definition: | The 17beta-isomer of estradiol. |
| Ontology: | ChEBI [CHEBI:16469] ( EBI ) |
| chemical treatment by environment: EC 1.14.13.39 (nitric oxide synthase) inhibitor |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | EC 1.14.13.39 (nitric oxide synthase) inhibitor |
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| Synonyms: | EC 1.14.13.39 (nitric oxide synthase) inhibitors, EC 1.14.13.39 inhibitor, EC 1.14.13.39 inhibitors, endothelium-derived relaxation factor-forming enzyme inhibitor, endothelium-derived relaxation factor-forming enzyme inhibitors, endothelium-derived relaxing factor synthase inhibitor, endothelium-derived relaxing factor synthase inhibitors, NADPH-diaphorase inhibitor, NADPH-diaphorase inhibitors, nitric oxide synthase (EC 1.14.13.39) inhibitor, nitric oxide synthase (EC 1.14.13.39) inhibitors, nitric oxide synthase inhibitor, nitric oxide synthase inhibitors, nitric oxide synthetase inhibitor, nitric oxide synthetase inhibitors, nitric-oxide synthetase inhibitor, nitric-oxide synthetase inhibitors, NO synthase inhibitor, NO synthase inhibitors |
| Definition: | An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of nitric oxide synthase (EC 1.14.13.39). |
| Ontology: | ChEBI [CHEBI:61908] ( EBI ) |
| Publication: | Murcia et al., 2016 |
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