tRNA Gene
mt-tl1
- ID
- ZDB-TRNAG-011205-6
- Name
- tRNA leucine 1 (TAA), mitochondrial
- Symbol
- mt-tl1 Nomenclature History
- Previous Names
- Type
- tRNA_gene
- Location
- Chr: MT Mapping Details/Browsers
- Description
- Predicted to enable triplet codon-amino acid adaptor activity.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sabharwal et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| Genomic | GenBank:AC024175 (1) | 16596 nt |
- Comparative Orthology
- Alliance
- Sabharwal, A., Kar, B., Restrepo-Castillo, S., Holmberg, S.R., Mathew, N.D., Kendall, B.L., Cotter, R.P., WareJoncas, Z., Seiler, C., Nakamaru-Ogiso, E., Clark, K.J., Ekker, S.C. (2021) The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells In Vitro and Zebrafish Disease Models In Vivo. The CRISPR journal. 4(6):799-821
- Chen, D., Zhang, Z., Chen, C., Yao, S., Yang, Q., Li, F., He, X., Ai, C., Wang, M., Guan, M.X. (2019) Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism. Nucleic acids research. 47(10):5341-5355
- Sabharwal, A., Sharma, D., Vellarikkal, S.K., Jayarajan, R., Verma, A., Senthivel, V., Scaria, V., Sivasubbu, S. (2018) Organellar transcriptome sequencing reveals mitochondrial localization of nuclear encoded transcripts. Mitochondrion. 46:59-68
- Broughton, R.E., Milam, J.E., and Roe, B.A. (2001) The complete sequence of the zebrafish (Danio rerio) mitochondrial genome and evolutionary patterns in vertebrate mitochondrial DNA. Genome research. 11(11):1958-1967
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