Search Ontology:
ChEBI

Remodelin

Term ID
CHEBI:747163
Synonyms
Definition
Remodelin is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells. Remodelin inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model. Remodelin enhances the healthspan in hutchinson-gilford progeria syndrome (HGPS) mouse model.
References
  • cas:949912-58-7
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from Remodelin
Phenotype where environments contain Remodelin
Phenotype modified by environments containing Remodelin
Phenotype affecting Remodelin
Human Disease Model
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