Search Ontology:
ChEBI

SN-011

Term ID
CHEBI:747183
Synonyms
Definition
SN-011 is a potent and selective mouse and human STING inhibitor, with an IC50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease.
References
  • cas:2249435-90-1
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from SN-011
Phenotype where environments contain SN-011
Phenotype modified by environments containing SN-011
Phenotype affecting SN-011
Human Disease Model
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