Search Ontology:
ChEBI

BRD6688

Term ID
CHEBI:234393
Synonyms
  • BRD 6688
  • BRD-6688
  • N-(2-amino-5-(pyridin-4-yl)phenyl)pyrrolidine-1-carboxamide
  • N-[2-amino-5-(4-pyridinyl)phenyl]-1-pyrrolidinecarboxamide
  • N-[2-amino-5-(4-pyridyl)phenyl]-1-pyrrolidinecarboxamide
  • N-[2-amino-5-(pyridin-4-yl)phenyl]pyrrolidine-1-carboxamide
Definition
A pyrrolidinecarboxamide that is N-phenylpyrrolidine-1-carboxamide substituted by amino and pyridin-4-yl groups at positions 2 and 5, respectively. It is a HDAC inhibitor (IC50 = 21 nM, 100 nM, and 11.48 muM for HDAC1, HDAC2, and HDAC3, respectively) and has shown to enhance cognition in mouse models.
References
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from BRD6688
Phenotype where environments contain BRD6688
Phenotype modified by environments containing BRD6688
Phenotype affecting BRD6688
Human Disease Model
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