Search Ontology:
ChEBI

CU-CPT22

Term ID
CHEBI:233358
Synonyms
  • 1416324-85-0
  • hexyl 3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate
Definition
CU-CPT22 is a potent protein complex of toll-like receptor 1 and 2 (TLR1/2) inhibitor, and competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 with a Ki of 0.41 uM. CU-CPT22 blocks Pam3CSK4-induced TLR1/2 activation with an IC50 of 0.58 uM.
References
  • CAS:1416324-85-0
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from CU-CPT22
Phenotype where environments contain CU-CPT22
Phenotype modified by environments containing CU-CPT22
Phenotype affecting CU-CPT22
Human Disease Model
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