GW405833

Term ID

CHEBI:92184

Synonyms

(2,3-dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-morpholin-4-yl-ethyl)-indol-1-yl]-methanone
(2,3-dichlorophenyl)-[5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1-indolyl]methanone
(2,3-dichlorophenyl)[5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1H-indol-1-yl]methanone
(2,3-dichlorophenyl){5-methoxy-2-methyl-3-[2-(morpholin-4-yl)ethyl]-1H-indol-1-yl}methanone
GW 405833
GW-405,833
GW-405833
L 768242
L-768,242
L-768242
L768242

Definition

A methylindole that is 2-methyl-1H-indole substituted by 2,3-dichlorobenzoyl, 2-(morpholin-4-yl)ethyl, and methoxy groups at positions 1, 3 and 5, respectively. It is a partial agonist of the cannabinoid CB₂ receptor (EC₅₀ = 0.65 nM).

References

cas:180002-83-9
lincs.smallmolecule:LSM-2217
pubmed:11972997
pubmed:15814101
pubmed:16316650
pubmed:19345493
pubmed:19552692
pubmed:20863899
pubmed:21737287
pubmed:23781122
pubmed:24721671
pubmed:26762784
pubmed:27432473
pubmed:27927913
pubmed:28592614
pubmed:30381869
pubmed:30542446
pubmed:30918343
pubmed:31806570
pubmed:31954990
pubmed:32952995
pubmed:35083004
pubmed:35513484
pubmed:35765518
pubmed:36697976
pubmed:37788055
pubmed:37891972
pubmed:38888628
wikipedia.en:GW-405,833

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from GW405833

Phenotype where environments contain GW405833

Phenotype modified by environments containing GW405833

Phenotype affecting GW405833

Human Disease Model