prednisone

Term ID

CHEBI:8382

Synonyms

• 1,2-Dehydrocortisone
• 1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
• 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
• Dehydrocortisone
• prednison
• prednisona
• prednisone
• prednisonum

Definition

A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a β-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

References

• cas:53-03-2
• drugbank:DB00635
• drugcentral:2253
• kegg.compound:C07370
• patent:US2579479
• patent:US2837464
• patent:US2897216
• patent:US3134718
• pubmed:10438974
• pubmed:15859934
• pubmed:18971570
• pubmed:23093541
• pubmed:23395281
• reaxys:2065301
• wikipedia.en:Prednisone

Ontology

ChEBI  ( EBI )

Resources

CTD