Search Ontology:
ChEBI

3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol

Term ID
CHEBI:64060
Synonyms
  • 1-(diphenylmethyl)-2-(4-(3-chlorophenyl)-1-piperazinyl)ethanol
  • 3-(4-(3-chlorophenyl)-1-piperazinyl)-1,1-diphenyl-2-propanol
  • 3-(4-(3-chlorophenyl)piperazin-1-yl)-1,1,-diphenyl-2-propanol
  • 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol
  • BRL 15572
  • BRL-15,572
  • BRL-15572
  • BRL15572
Definition
An N-alkylpiperazine that is 1-(3-chlorophenyl)piperazine carrying a 3,3-diphenyl-2-hydroxyprop-1-yl group at position 4. A selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types.
References
  • cas:734517-40-9
  • chemspider:2887678
  • lincs.smallmolecule:LSM-1618
  • pubmed:10854905
  • pubmed:11172936
  • pubmed:11249960
  • pubmed:11750791
  • pubmed:19014464
  • pubmed:19182382
  • pubmed:19721332
  • pubmed:19837141
  • pubmed:20385119
  • pubmed:20863828
  • pubmed:21473863
  • pubmed:21699915
  • pubmed:23583574
  • pubmed:24134630
  • pubmed:25502305
  • pubmed:30904722
  • pubmed:9303567
  • pubmed:9303568
  • pubmed:9865532
  • reaxys:9004321
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol
Phenotype where environments contain 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol
Phenotype modified by environments containing 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol
Phenotype affecting 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol
Human Disease Model