TALEN

TALEN1-tmem67

ID

ZDB-TALEN-240314-1

Name

TALEN1-tmem67

Previous Names

None

Target

tmem67 (1)

Target Sequence 1

5' - TGGTCACCCAGGATGGAT - 3'

Target Sequence 2

5' - TTCCCCACAGTTCCAGGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
xu095	tmem67

Expression

Gene expression in Wild Types + TALEN1-tmem67

No data available

Phenotype

Phenotype resulting from TALEN1-tmem67

No data available

Phenotype of all Fish created by or utilizing TALEN1-tmem67

Phenotype	Fish	Conditions	Figures
kidney increased size, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 3 from Zhu et al., 2021
kidney tmem67 expression decreased amount, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 3 from Zhu et al., 2021
kidney cep290 expression increased amount, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 3 from Zhu et al., 2021
pronephros cilium decreased amount, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 2 from Zhu et al., 2021
multi-ciliated epithelial cell 9+2 motile cilium increased amount, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 5 from Zhu et al., 2021
pronephros cilium decreased length, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 2 from Zhu et al., 2021
kidney cilium decreased length, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 6, Fig. 7 from Zhu et al., 2021
kidney cystic, ameliorated	tmem67^xu095/xu095 (WIK)	chemical treatment by gavage: sirolimus	Fig. 8 from Zhu et al., 2021
whole organism curved ventral, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 1, Fig. 3 from Zhu et al., 2021
kidney cystic, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 3, Fig. 7, Fig. 8 from Zhu et al., 2021
TOR signaling increased magnitude, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 8 from Zhu et al., 2021
kidney mks1 expression increased amount, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 3 from Zhu et al., 2021
pronephros cystic, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 1, Fig. 2 from Zhu et al., 2021
TOR signaling magnitude, ameliorated	tmem67^xu095/xu095 (WIK)	chemical treatment by gavage: sirolimus	Fig. 8 from Zhu et al., 2021
kidney cc2d2a expression increased amount, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 3 from Zhu et al., 2021
whole organism tmem67 expression decreased amount, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 1 from Zhu et al., 2021
kidney epithelial cell cell population proliferation increased occurrence, abnormal	tmem67^xu095/xu095 (WIK)	standard conditions	Fig. 4, Fig. 8 from Zhu et al., 2021
kidney cystic, ameliorated	tmem67^xu095/xu095; mtor^xu015Gt/+ (WIK)	standard conditions	Fig. 8 from Zhu et al., 2021
kidney epithelial cell cell population proliferation increased occurrence, ameliorated	tmem67^xu095/xu095; mtor^xu015Gt/+ (WIK)	standard conditions	Fig. 8 from Zhu et al., 2021

Citations