TALEN

TALEN1-her1

ID

ZDB-TALEN-180911-1

Name

TALEN1-her1

Previous Names

None

Target

her1 (1)

Target Sequence 1

5' - TCCGTCTAGATCTT - 3'

Target Sequence 2

5' - CCGGTCTCTCCGTTTCTTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genome Build: GRCz11Chromosome: 5

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf2173	her1

Expression

Gene expression in Wild Types + TALEN1-her1

No data available

Phenotype

Phenotype resulting from TALEN1-her1

No data available

Phenotype of all Fish created by or utilizing TALEN1-her1

Phenotype	Fish	Conditions	Figures
fast muscle cell decreased amount, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
vertebra morphology, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	text only from Lleras-Forero et al., 2020
trunk musculature lesioned, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. S1 from Lleras-Forero et al., 2020
skeletal muscle cell shape, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. S2 from Lleras-Forero et al., 2020
skeletal muscle cell disorganized, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. S2 from Lleras-Forero et al., 2020
trunk musculature morphology, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
segmental plate anterior side mespba expression spatial pattern, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 from LLeras Forero et al., 2018
muscle attachment process quality, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. S1 from Lleras-Forero et al., 2020
segmental plate her7 expression spatial pattern, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 from LLeras Forero et al., 2018
muscle pioneer en2a expression spatial pattern, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 from LLeras Forero et al., 2018
slow muscle cell disorganized, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
vertebral column increased curvature, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 2 from Lleras-Forero et al., 2020
vertebra fused with vertebra, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	text only from Lleras-Forero et al., 2020 Fig. 2 from LLeras Forero et al., 2018
skeletal muscle cell length, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. S2 from Lleras-Forero et al., 2020
fast muscle cell decreased area, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
somitogenesis process quality, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 2 from LLeras Forero et al., 2018
trunk musculature decreased volume, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 3 from Lleras-Forero et al., 2020
somite border spatial pattern, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 , Fig. 2 from LLeras Forero et al., 2018
fast muscle cell disorganized, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
myotome compartment boundary amorphous, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. S1 from Lleras-Forero et al., 2020
skeletal muscle cell decreased amount, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. S2 from Lleras-Forero et al., 2020
somite xirp2a expression spatial pattern, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 2 from LLeras Forero et al., 2018
segmental plate anterior side mespba expression decreased amount, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 from LLeras Forero et al., 2018
somite border disorganized, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 , Fig. 2 from LLeras Forero et al., 2018
centrum irregular spatial pattern, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}; hu6867Tg	standard conditions	Fig. 5 from LLeras Forero et al., 2018
centrum morphology, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}; hu6867Tg	standard conditions	Fig. 5 from LLeras Forero et al., 2018
myotome compartment boundary disorganized, abnormal	her7^{hu2526/hu2526}; her1^{zf2173/zf2173}; hu7478Tg; nknkgsaizgffm1954AGt	standard conditions	Fig. S3 from Lleras-Forero et al., 2020
fast muscle cell decreased amount, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
vertebra morphology, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	text only from Lleras-Forero et al., 2020
trunk musculature lesioned, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. S1 from Lleras-Forero et al., 2020
slow muscle cell increased thickness, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
skeletal muscle cell shape, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. S2 from Lleras-Forero et al., 2020
skeletal muscle structure, cavities, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
skeletal muscle cell disorganized, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. S2 from Lleras-Forero et al., 2020
trunk musculature morphology, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
vertebral column increased curvature, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 2 from Lleras-Forero et al., 2020
slow muscle cell fused with slow muscle cell, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
segmental plate mespba expression absent, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 from LLeras Forero et al., 2018
muscle pioneer en2a expression spatial pattern, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 from LLeras Forero et al., 2018
segmental plate her7 expression spatial pattern, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 from LLeras Forero et al., 2018
skeletal muscle cell length, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. S2 from Lleras-Forero et al., 2020
slow muscle cell disorganized, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
vertebra fused with vertebra, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	text only from Lleras-Forero et al., 2020 Fig. 2 from LLeras Forero et al., 2018
muscle attachment process quality, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. S1 from Lleras-Forero et al., 2020
slow muscle cell decreased amount, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
myotome compartment boundary amorphous, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. S1 from Lleras-Forero et al., 2020
somitogenesis process quality, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 2 from LLeras Forero et al., 2018
trunk musculature decreased volume, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 3 from Lleras-Forero et al., 2020
segmental plate anterior side her7 expression absent, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 from LLeras Forero et al., 2018
fast muscle cell disorganized, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 4 from Lleras-Forero et al., 2020
somite border spatial pattern, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 , Fig. 2 from LLeras Forero et al., 2018
somite xirp2a expression spatial pattern, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 2 from LLeras Forero et al., 2018
somite border disorganized, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. 1 , Fig. 2 from LLeras Forero et al., 2018
skeletal muscle cell decreased amount, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}	standard conditions	Fig. S2 from Lleras-Forero et al., 2020
myotome compartment boundary disorganized, abnormal	her7^{hu2526/hu2526}; tbx6^{sa38869/sa38869}; her1^{zf2173/zf2173}; hu7478Tg; nknkgsaizgffm1954AGt	standard conditions	Fig. S3 from Lleras-Forero et al., 2020

Citations

Include unpublished citations

LLeras Forero, L., Narayanan, R., Huitema, L.F.A., VanBergen, M., Apschner, A., Peterson-Maduro, J., Logister, I., Valentin, G., Morelli, L.G., Oates, A., Schulte-Merker, S. (2018) Segmentation of the zebrafish axial skeleton relies on notochord sheath cells and not on the segmentation clock. eLIFE. 7

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