PUBLICATION

Expression patterns of zebrafish sox11A, sox11B and sox21

Authors
Rimini, R., Beltrame, M., Argenton, F., Szymczak, D., Cotelli, F., and Bianchi, M.E.
ID
ZDB-PUB-991123-1
Date
1999
Source
Mechanisms of Development   89(1-2): 167-171 (Journal)
Registered Authors
Argenton, Francesco, Beltrame, Monica, Cotelli, Franco, Rimini, Rebecca
Keywords
brain; noi; midbrain; hindbrain; HMG-box; maternal genes; transcription factors.
MeSH Terms
  • Amino Acid Sequence
  • Animals
  • Blastocyst
  • Brain/embryology
  • Cloning, Molecular
  • Embryo, Nonmammalian
  • Gene Expression Regulation, Developmental*
  • High Mobility Group Proteins/genetics*
  • High Mobility Group Proteins/metabolism
  • Molecular Sequence Data
  • Neoplasm Proteins/genetics*
  • Neoplasm Proteins/metabolism
  • SOX Transcription Factors
  • SOXC Transcription Factors
  • Sequence Homology, Amino Acid
  • Transcription, Genetic
  • Zebrafish/embryology*
  • Zebrafish/genetics*
  • Zebrafish Proteins*
PubMed
10559493 Full text @ Mech. Dev.
Abstract
We have cloned three sox genes in zebrafish (Danio rerio), one related to human and chicken SOX21, and two related to mammalian and chicken Sox-11. Zebrafish sox21, sox11A and sox11B transcripts are accumulated in the egg, are present in all cells until gastrulation and become restricted later to the developing central nervous system (CNS); expression in adults is undetectable. sox21 is expressed in the forebrain, midbrain and hindbrain, but maximally at the midbrain-hindbrain junction; sox11A,B have a widespread and dynamic expression in the CNS, but in contrast to sox21 are absent at the midbrain-hindbrain boundary.
Genes / Markers
Figures
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Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping