PUBLICATION

Heat shock produces periodic somitic disturbances in the zebrafish embryo

Authors
Roy, M.N., Prince, V.E., and Ho, R.K.
ID
ZDB-PUB-990824-25
Date
1999
Source
Mechanisms of Development   85(1-2): 27-34 (Journal)
Registered Authors
Ho, Robert K., Prince, Victoria E.
Keywords
zebrafish; somitogenesis; heat shock; segmentation; motoneurons
MeSH Terms
  • Animals
  • Cell Cycle
  • Cell Differentiation
  • Embryo, Nonmammalian/physiology*
  • Hot Temperature/adverse effects*
  • Somites/pathology*
  • Somites/physiology
  • Zebrafish/embryology*
PubMed
10415344 Full text @ Mech. Dev.
Abstract
Environmental influences are known to produce segmental defects in a variety of organisms. In this paper we report upon segmental aberrations produced by brief heat shocks delivered to developing zebrafish embryos. The initial defects in the segmental pattern of somitic boundaries and motoneuron axon outgrowth were usually observed five somites caudal to the somite which was forming at the time of heat shock application. Segmental defects in zebrafish embryos exposed to a single heat shock treatment can occur in a periodic pattern similar to the multiple disturbances observed to occur in chick embryos. These data are discussed with regard to models involving cell cycle synchrony or 'clock and wavefront' schemes in the process of somitogenesis.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping