PUBLICATION
sox30: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis
- Authors
- De Martino, S.P., Errington, F., Ashworth, A., Jowett, T., and Austin, C.A.
- ID
- ZDB-PUB-990628-17
- Date
- 1999
- Source
- Development genes and evolution 209(6): 357-362 (Journal)
- Registered Authors
- Austin, Caroline Ann, Jowett, Trevor
- Keywords
- sox; zebrafish; development; brain; midbrain-hindrain boundary
- MeSH Terms
-
- RNA/genetics
- RNA/metabolism
- Gene Expression Regulation, Developmental
- SOXB2 Transcription Factors
- Zebrafish Proteins*
- Nervous System/embryology
- Nervous System/metabolism
- Animals
- Tissue Distribution
- Sequence Homology, Amino Acid
- Mesencephalon/embryology
- Mesencephalon/metabolism
- Sequence Analysis, DNA
- Evolution, Molecular
- In Situ Hybridization
- Amino Acid Sequence
- High Mobility Group Proteins/genetics*
- Molecular Sequence Data
- Sequence Alignment
- Cloning, Molecular
- Zebrafish
- DNA, Complementary/chemistry
- DNA, Complementary/genetics
- DNA-Binding Proteins/genetics*
- Embryo, Nonmammalian/metabolism
- Phylogeny
- Rhombencephalon/embryology
- Rhombencephalon/metabolism
- PubMed
- 10370117 Full text @ Dev. Genes Evol.
Citation
De Martino, S.P., Errington, F., Ashworth, A., Jowett, T., and Austin, C.A. (1999) sox30: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis. Development genes and evolution. 209(6):357-362.
Abstract
The Sox family of proteins is thought to act to regulate gene expression in a wide variety of developmental processes. Here we describe the cloning of sox30, a novel sox gene from the zebrafish (Danio rerio). In situ hybridization shows that sox30 is expressed in a restricted manner at the boundary between the midbrain and hindbrain during nervous system development. This expression pattern is in direct contrast to that of most other neuronally expressed Sox genes which are expressed throughout the nervous system.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping