PUBLICATION
The metabolism of phenol and substituted phenols in zebra fish
- Authors
- Kasokat, T., Nagel, R., and Urich, K.
- ID
- ZDB-PUB-990512-4
- Date
- 1987
- Source
- Xenobiotica; the fate of foreign compounds in biological systems 17(10): 1215-1221 (Journal)
- Registered Authors
- Nagel, Roland
- Keywords
- none
- MeSH Terms
-
- Animals
- Chlorophenols/metabolism
- Chromatography, High Pressure Liquid
- Chromatography, Thin Layer
- Cresols/metabolism
- Cyprinidae/metabolism*
- Female
- Nitrophenols/metabolism
- Pentachlorophenol/metabolism
- Phenols/metabolism*
- Zebrafish/metabolism*
- PubMed
- 3424868 Full text @ Xenobiotica
Citation
Kasokat, T., Nagel, R., and Urich, K. (1987) The metabolism of phenol and substituted phenols in zebra fish. Xenobiotica; the fate of foreign compounds in biological systems. 17(10):1215-1221.
Abstract
1. The metabolism of five phenols in zebra fish was studied after uptake from the medium. The results showed no qualitative differences to other Cyprinid fish species, only the oxidation rate seemed to be lower. 2. Phenyl glucuronide, phenyl sulphate, and quinol sulphate were identified as metabolites of phenol. 3. Identified metabolites of 2-cresol were 2-cresyl glucuronide, 2-cresyl sulphate, and 2-hydroxybenzoic acid in trace amounts. 4. Only the glucuronide and sulphate conjugates were detected as metabolites of 4-nitrophenol, 4-chlorophenol, and pentachlorophenol.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping