PUBLICATION
Maternal mRNA localization of zebrafish DAZ-like gene
- Authors
- Maegawa, S., Yasuda, K., and Inoue, K.
- ID
- ZDB-PUB-990506-5
- Date
- 1999
- Source
- Mechanisms of Development 81(1-2): 223-226 (Journal)
- Registered Authors
- Inoue, Kunio, Maegawa, Shingo
- Keywords
- none
- MeSH Terms
-
- Male
- Ovary/metabolism
- Animals
- Testis/metabolism
- Zebrafish/embryology*
- In Situ Hybridization
- Molecular Sequence Data
- RNA, Messenger/metabolism*
- Blotting, Northern
- RNA-Binding Proteins/analysis
- RNA-Binding Proteins/genetics*
- RNA-Binding Proteins/metabolism
- Female
- Tissue Distribution
- Gene Library
- Sequence Homology, Amino Acid
- Models, Genetic
- PubMed
- 10330505 Full text @ Mech. Dev.
Citation
Maegawa, S., Yasuda, K., and Inoue, K. (1999) Maternal mRNA localization of zebrafish DAZ-like gene. Mechanisms of Development. 81(1-2):223-226.
Abstract
Members of the DAZ gene family encode RNA-binding proteins and have been shown to play a pivotal role in gametogenesis. In Xenopus, a DAZ-like gene encodes an RNA component of the germ plasm. We have identified a zebrafish DAZ homologue, zDazl. zDazl mRNA was expressed in gonads of both sexes. In ovary, it was localized in the cortex of oocytes. At the onset of embryogenesis, maternal zDazl mRNA was detected at the vegetal pole. It migrated toward blastomeres through cytoplasmic streams as early embryogenesis proceeded. This is the first report showing maternal mRNA localization at the vegetal pole in fish and the existence of mRNA streams in the yolk cytoplasm.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping