PUBLICATION

Cone contributions to the photopic spectral sensitivity of the zebrafish ERG

Authors
Hughes, A., Saszik, S., Bilotta, J., DeMarco, Jr., P.J., and Patterson II, W.F.
ID
ZDB-PUB-981209-15
Date
1998
Source
Visual neuroscience   15: 1029-1037 (Journal)
Registered Authors
Bilotta, Joe
Keywords
Danio rerio; electroretinogram; color opponency; ultraviolet cones
MeSH Terms
  • Adaptation, Physiological/physiology
  • Animals
  • Color Perception/physiology*
  • Electroretinography*
  • Female
  • Male
  • Models, Biological
  • Retinal Cone Photoreceptor Cells/physiology*
  • Zebrafish/physiology*
PubMed
9839967 Full text @ Vis. Neurosci.
Abstract
Microspectrophotometry studies show that zebrafish (Danio rerio) possess four cone photopigments. The purpose of this study was to determine the cone contributions to the zebrafish photopic increment threshold spectral-sensitivity function. Electroretinogram (ERG) b-wave responses to monochromatic lights presented on a broadband or chromatic background were obtained. It was found that under the broadband background condition, the zebrafish spectral-sensitivity function showed several peaks that were narrower in sensitivity compared to the cone spectra. The spectral-sensitivity function was modeled with L - M and M - S opponent interactions and nonopponent S- and U-cone mechanisms. Using chromatic adaptation designed to suppress the contribution of the S-cones, a strong U-cone contribution to the spectral-sensitivity function was revealed, and the contributions of the S-cones to the M - S mechanism were reduced. These results show that the b-wave component of the ERG receives input from all four cone types and appears to reflect color opponent mechanisms. Thus, zebrafish may possess the fundamental properties necessary for color vision.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes