PUBLICATION

The zebrafish organizer

Authors
Schier, A.F. and Talbot, W.S.
ID
ZDB-PUB-981006-6
Date
1998
Source
Current opinion in genetics & development   8: 464-471 (Review)
Registered Authors
Schier, Alexander, Talbot, William S.
Keywords
none
MeSH Terms
  • Animals
  • Humans
  • Zebrafish/embryology*
PubMed
9729724 Full text @ Curr. Opin. Genet. Dev.
Abstract
Signals from the organizer play a crucial role in patterning the vertebrate embryo. Recent molecular analysis of zebrafish mutations has established an essential role for BMP2 and chordin in organizer function and has identified one-eyed pinhead as a novel EGF-like gene involved in prechordal plate and endoderm formation. In addition, embryological studies have suggested that the zebrafish organizer is induced by extraembryonic cues and have defined two novel organizing centers that pattern the nervous system along the anterior-posterior axes.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping