PUBLICATION
Toxicity of complex chemical mixtures: acute and long-term effects on different life states of zebrafish (Brachydanio rerio)
- Authors
- Ensenbach, U. and Nagel, R.
- ID
- ZDB-PUB-961014-292
- Date
- 1995
- Source
- Ecotoxicology and environmental safety 30: 151-157 (Journal)
- Registered Authors
- Nagel, Roland
- Keywords
- none
- MeSH Terms
-
- Aniline Compounds/toxicity*
- Animals
- Behavior, Animal/drug effects
- Dose-Response Relationship, Drug
- Fresh Water
- Hexachlorocyclohexane/toxicity*
- Lethal Dose 50
- Survival Rate
- Time Factors
- Water Pollutants, Chemical/toxicity*
- Zebrafish/abnormalities
- Zebrafish/growth & development*
- Zebrafish/physiology
- PubMed
- 7539369 Full text @ Ecotoxicol. Environ. Saf.
Citation
Ensenbach, U. and Nagel, R. (1995) Toxicity of complex chemical mixtures: acute and long-term effects on different life states of zebrafish (Brachydanio rerio). Ecotoxicology and environmental safety. 30:151-157.
Abstract
Acute and long-term toxicity of 3,4-dichloroaniline and lindane to zebrafish were examined in tap water and water from the Rhine River and the toxicity of the binary mixture 3,4- dichloroaniline/lindane in tap water was investigated. The acute toxicity of 3,4-dichloroaniline and lindane was not influenced by the complex matrix of river water compared with tap water. The binary mixture of 3,4-dichloroaniline and lindane demonstrated an additive effect in the acute test. The survival rate of early life stages in river water was reduced by lindane (80 micrograms/liter), whereas the effects of 3,4- dichloroaniline on survival and growth were visible but not significant. The binary mixture of 2 micrograms/liter, 3,4- dichloroaniline and 40 micrograms/liter lindane in tap water had an influence on growth on the early life stages of zebrafish.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping