PUBLICATION
A zebrafish homeobox-containing gene with embryonic transcription
- Authors
- Eiken, H.G., Njolstad, P.R., Molven, A., and Fjose, A.
- ID
- ZDB-PUB-961014-263
- Date
- 1987
- Source
- Biochemical and Biophysical Research Communications 149: 1165-1171 (Journal)
- Registered Authors
- Fjose, Anders, Molven, Anders
- Keywords
- none
- MeSH Terms
-
- Animals
- Base Sequence
- DNA, Recombinant
- Drosophila melanogaster/genetics
- Embryo, Nonmammalian/analysis
- Embryonic and Fetal Development
- Fishes/embryology
- Fishes/genetics*
- Genes, Homeobox*
- Molecular Sequence Data
- Nucleic Acid Hybridization
- Poly A/analysis
- RNA, Messenger/analysis
- Sequence Homology, Nucleic Acid
- PubMed
- 2892487 Full text @ Biochem. Biophys. Res. Commun.
Citation
Eiken, H.G., Njolstad, P.R., Molven, A., and Fjose, A. (1987) A zebrafish homeobox-containing gene with embryonic transcription. Biochemical and Biophysical Research Communications. 149:1165-1171.
Abstract
A genomic library of zebrafish (Brachydanio rerio) was constructed and screened with homeobox-containing probes. One of the strongly cross-hybridizing clones was characterized by DNA sequencing. The deduced amino acid sequence exhibits extensive homology (greater than 80%) relative to the Antennapedia-class of Drosophila homeobox sequences. Characterization of the gene with respect to expression demonstrated that two transcripts of 2.1 and 1.4 kb, respectively, are present in embryonic poly (A+) RNA. The highest concentration of the two RNA species was observed in embryos which have terminated the process of somite formation.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping