PUBLICATION

A zebrafish homeobox-containing gene with embryonic transcription

Authors
Eiken, H.G., Njolstad, P.R., Molven, A., and Fjose, A.
ID
ZDB-PUB-961014-263
Date
1987
Source
Biochemical and Biophysical Research Communications   149: 1165-1171 (Journal)
Registered Authors
Fjose, Anders, Molven, Anders
Keywords
none
MeSH Terms
  • Animals
  • Base Sequence
  • DNA, Recombinant
  • Drosophila melanogaster/genetics
  • Embryo, Nonmammalian/analysis
  • Embryonic and Fetal Development
  • Fishes/embryology
  • Fishes/genetics*
  • Genes, Homeobox*
  • Molecular Sequence Data
  • Nucleic Acid Hybridization
  • Poly A/analysis
  • RNA, Messenger/analysis
  • Sequence Homology, Nucleic Acid
PubMed
2892487 Full text @ Biochem. Biophys. Res. Commun.
Abstract
A genomic library of zebrafish (Brachydanio rerio) was constructed and screened with homeobox-containing probes. One of the strongly cross-hybridizing clones was characterized by DNA sequencing. The deduced amino acid sequence exhibits extensive homology (greater than 80%) relative to the Antennapedia-class of Drosophila homeobox sequences. Characterization of the gene with respect to expression demonstrated that two transcripts of 2.1 and 1.4 kb, respectively, are present in embryonic poly (A+) RNA. The highest concentration of the two RNA species was observed in embryos which have terminated the process of somite formation.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping