ZFIN ID: ZDB-PUB-961014-1261
Something's fishy here--Rethinking cell movements and cell fate in the zebrafish embryo
Wilson, E.T., Helde, K.A., and Grunwald, D.J.
Date: 1993
Source: Trends in genetics : TIG   9: 348-352 (Review)
Registered Authors: Grunwald, David, Helde, Kathryn, Wilson, Ellen
Keywords: none
MeSH Terms:
  • Animals
  • Cell Differentiation
  • Cell Movement
  • Zebrafish/embryology*
PubMed: 8273149 Full text @ Trends Genet.
A recent paper has challenged the prevailing view that zebrafish blastomeres undergo extensive cell mixing and are unrestricted in their cell fates during early development. Here, we offer a model that resolves apparent contradictions between studies that have examined the origins of cell fate in the zebrafish embryo. The model reconsiders cell movements during epiboly, and how cell mixing, or the lack of it, can affect the predictability of cell fate.