The development of photoreceptors in the zebrafish, Brachydanio rerio. I. Structure
- Branchek, T. and BreMiller, R.
- The Journal of comparative neurology 224: 107-115 (Journal)
- Registered Authors
- BreMiller, Ruth
- MeSH Terms
- Cell Differentiation*
- Fishes/anatomy & histology*
- Microscopy, Electron
- Photoreceptor Cells/cytology*
- Rod Cell Outer Segment/cytology
- 6715574 Full text @ J. Comp. Neurol.
Branchek, T. and BreMiller, R. (1984) The development of photoreceptors in the zebrafish, Brachydanio rerio. I. Structure. The Journal of comparative neurology. 224:107-115.
Morphological development of photoreceptors in the central retina of the zebrafish, Brachydanio rerio, was studied by using light and electron microscopic techniques. Outer segments (OS) first appeared at 2.5 days postfertilization (d2.5). On d3, synaptic elaborations were seen. By d8, two OS types were present and were identified as cones. The first indication of rod formation was also evidenced at this time, when vitreally positioned nuclei were observed and rodlike cells were infrequently detected in electron micrographs. At d12, the full complement of zebrafish photoreceptors, rods and four cone types, was identified. From this time on cells grew until adult dimensions were reached at d24. These structural observations are consistent with results of functional studies which utilized physiological and behavioral techniques.
Genes / Markers
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Engineered Foreign Genes